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As seen in: The American Journal of Human Genetics
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Articles

Epigenome-wide meta-analysis of BMI in nine cohorts: Examining the utility of epigenetically predicted BMI

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By Whitney L. Do, Ellen W Demerath, Childrens Minnesota
| The American Journal of Human Genetics Verified
Summary This study sought to examine the association between DNA methylation and body mass index (BMI) and the potential of BMI-associated cytosine-phosphate-guanine (CpG) sites to provide information about metabolic health. We pooled summary statistics from six trans-ethnic epigenome-wide association studies (EWASs) of BMI representing nine cohorts (n = 17,034), replicated these findings in the Women’s Health Initiative (WHI, n = 4,822), and developed an epigenetic prediction score of BMI.
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