Chinonso Obidike on Muck Rack

Chinonso Obidike

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LPS‐mediated release of ATP from urothelial cells occurs by lysosomal exocytosis

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By Brittany Chavez, Andrew Silberfeld, Chinonso Obidike, Stephanie Daugherty
| Wiley
Background While numerous studies have confirmed ATP's importance in bladder physiology/pathophysiology, the literature is still conflicted regarding the mechanism of ATP release from the urothelium. Multiple mechanisms have been identified including non‐vesicular release via pannexin channels as well as vesicular release via a mechanism blocked by botulinum toxin.
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