Chloé Ben Ali on Muck Rack

Chloé Ben Ali

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Articles

Podocyte dysfunction driven by heme in sickle-cell nephropathy - Scientific Reports

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By Antoine Morel, Pablo Bartolucci, Vincent Audard, Chloé Ben Ali
| Nature Verified
Abstract Sickle-cell disease (SCD) is characterized by vaso-occlusive crises and chronic hemolytic anemia, leading to tissue damage affecting various organs, including the kidneys. Hemolysis contributes to sickle-cell nephropathy (SCN) but the molecular mechanisms underlying the intravascular hemolysis and heme release involved in podocyte damage leading to proteinuria and chronic kidney disease remain uncertain.
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