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Chloe L Thio on Muck Rack

Chloe L Thio

As seen in: Nature, Wiley, MDPI, Genome Medicine, BioRxiv, The American Journal of Human Genetics, The Lancet
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Articles

New potent HBV replication inhibitors for the management of chronic hepatitis B are needed - Nature Reviews Gastroenterology & Hepatology

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By Fabien Zoulim, Charles Rice, Chloe L Thio, Robert G. Gish, Jordan J. Feld
| Nature Verified
With several drugs in use that inhibit the hepatitis B virus polymerases (nucleos(t)ide analogues (or NUCs)), some argue that new direct-acting antiviral drugs, and new NUCs in particular, are not necessary. Here, we make the counter-argument that additional direct-acting antiviral drugs that can potently suppress hepatitis B virus replication, ideally via distinct mechanisms, are still needed and can provide additional therapeutic benefits.
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Intracellular Host Restriction of Hepatitis B Virus Replication

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By Prakriti Sinha, Chloe L Thio, Ashwin Balagopal
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Pathogen exposure misclassification can bias association signals in GWAS of infectious diseases when using population-based common control subjects

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By Dylan Duchen, Candelaria Vergara, Chloe L Thio, Prosenjit Kundu
| The American Journal of Human Genetics Verified
Visscher P.M. Wray N.R. Zhang Q. Sklar P. McCarthy M.I. Brown M.A. Yang J. 10 Years of GWAS Discovery: Biology, Function, and Translation. Am. J. Hum. Genet. 2017; 101: 5-22 Clayton D.G. Cardon L.R. Craddock N. Deloukas P. Duncanson A. Kwiatkowski D.P. McCarthy M.I. Ouwehand W.H. Samani N.J. et al. Wellcome Trust Case Control Consortium Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature. 2007; 447: 661-678 Zhou W. Nielsen J.B. Fritsche L.G. Dey R.
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