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Chloé Porcheron

As seen in: The BMJ
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Articles

Blockade of colon cancer metastasis via single and double silencing of PCSK7/PCSK9: enhanced T cells cytotoxicity in mouse and human

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By Mailys Le Dévéhat, Hadi Bayat, Chloé Porcheron, Anna Roubtsova
| The BMJ Verified
Previously, we showed that in mouse B16 melanoma cells, silencing liver and endogenous Pcsk9 expression reduced cellular proliferation, migration, growth in vitro and liver tumor metastasis in C57BL/6 mice in vivo.28 32 Thus, both liver and intrinsic tumor-produced PCSK9 are critical in facilitating melanoma growth and/or migration.
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