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Chong Chyn Chua on Muck Rack

Chong Chyn Chua

As seen in: BioRxiv, The Lancet, Texas Medical Center
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Articles

"Treatment-Free Remission After Ceasing Venetoclax-Based Therapy in Pat" by Chong Chyn Chua, Danielle Hammond et al.

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By Chong Chyn Chua
| Texas Medical Center
Abstract The clinical benefit of adding venetoclax (VEN) to hypomethylating agents or low-dose cytarabine in older and/or unfit patients with newly diagnosed acute myeloid leukemia (AML) has been confirmed in phase 3 studies. With the increased uptake of VEN-based therapies for patients with AML, a pertinent question is whether treatment can be safely ceased among patients who have achieved sustained remission.
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Single-cell Rapid Capture Hybridization sequencing (scRaCH-seq) to reliably detect isoform usage and coding mutations in targeted genes at a single-cell level

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By Jafar S. Jabbari, Luyi Tian, Chong Chyn Chua, Hongke Peng
| BioRxiv
Abstract Single-cell long-read sequencing has transformed our understanding of isoform usage and the mutation heterogeneity between cells. Despite unbiased in-depth analysis, the low sequencing throughput often results in insufficient read coverage thereby limiting our ability to perform mutation calling for specific genes.
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Taking a step forward in CAR T-cell therapy for acute myeloid leukaemia and myelodysplastic syndrome

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By Chong Chyn Chua
| The Lancet Verified
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