Abstract Mpox (formerly monkeypox) is a zoonotic disease caused by the monkeypox virus (MPXV). In January 2022, the World Health Organization (WHO) reported a global outbreak in mpox cases across all six WHO regions with a high incidence rate of human-to-human transmission. A frequent prodrome symptom of MPXV infection is fever, with a febrile range of 38.3 to 40.5 °C.