Christer Abou Anny

1 Introduction Cellular physiology is tightly regulated by posttranslational modifications (PTMs), which act as molecular switches to control protein function, localization, expression level, and partner interactions.[1] Dysregulation of PTMs is a hallmark of many human diseases, yet dissecting their precise roles at individual protein sites remains challenging.[2] A major limitation arises from the difficulty of directly visualizing specific PTMs on a given protein within its native cellular...