Christian Morel on Muck Rack

Christian Morel

Marly-le-Roi
As seen in: Nature, ProQuest, Le Républicain Lorrain, L'Est Républicain, Vosges Matin, Option Finance
Journaliste Consultant Communication Le Républicain Lorrain Est Republicain et Vosges Matin. CUEJ Strasbourg.
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Articles

The HDAC inhibitor romidepsin renders liver cancer vulnerable to RTK targeting and immunologically active - Nature Communications

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By Celia Sequera, Delphine Debayle, Sandro Nuciforo, Jean-William Dupuy, Frédéric Saltel, Markus H. Heim, Sophie Vasseur, Fabienne Guillaumond, Jean-Paul Borg, Christian Morel
| Nature
Abstract Histone deacetylases (HDACs) are epigenetic regulators frequently altered in cancer. Here we report that overexpression of HDAC1/2 occurs in Hepatocellular Carcinoma (HCC) patients, correlating with poor prognosis. We show that romidepsin, a class-I HDAC inhibitor, elicits a combinatorial perturbation of distinct molecular processes in HCC cells, altering lipid composition, mitotic spindle machinery, and levels of cell cycle/survival signals.
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The SNR of time-of-flight positron emission tomography data for joint reconstruction of the activity and attenuation images

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By Christian Morel, Johan Nuyts, Michel Defrise, Paul Lecoq
| hal.science
The SNR of time-of-flight positron emission tomography data for joint reconstruction of the activity and attenuation images Mots clés SNR positron emission tomography reconstruction variance Fichier sous embargo 0 ― 8 ― 10 Année Mois Jours Avant la publication samedi 28 septembre 2024
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