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Christine Baxter

As seen in: Nature
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Articles by Christine Baxter

Oral bacterial lysate treatment for prevention of recurrent wheeze following severe bronchiolitis: protocol for an international multicentre randomised, placebo-controlled trial (BLIPA)

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By Abigail Whitehouse, Stephanie T. Yerkovich, Clare Robinson, Mia Johnson, Keith Grimwood, Steven M McPhail, Hiran Selvadurai, Danielle F. Wurzel, Gabrielle B. McCallum, Stephen Turner, Graham Roberts, Debby Bogaert, Jürgen Schwarze, Atul Gupta, Julie M. Marchant, Shane George, Peter Morris, Hannah O’Farrell, Robyn L. Marsh, Margaret S. McElrea, Anne B. Chang, Jonathan Grigg, Christine Baxter
| Nature Verified
Abstract Bronchiolitis is a common condition caused by a viral acute lower respiratory infection (ALRI) in infants. Severe bronchiolitis requiring hospitalisation is associated with increased risk of preschool wheeze and school-age asthma. Early exposure to microbial products modulating immune system development may help prevent later wheeze. Thus, this study evaluates whether an oral bacterial lysate after bronchiolitis hospitalisation reduces subsequent wheezing episodes.
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