Christopher Bailey
As seen in:
Environmental Health Perspectives,
Nature,
Wiley Online Library,
BioRxiv,
The Indianapolis Star,
Canadian Journal of Infectious Diseases & Medical Microbiology,
Radiological Society of North America,
Chemistry World,
International Journal of Numerical Methods for Heat & Fluid Flow,
Journal of the American College of Radiology
and
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Articles by Christopher Bailey
Sphingosine-1-phosphate receptor modulators resensitize FLT3-ITD acute myeloid leukemia cells with NRAS mutations to FLT3 inhibitors
Abstract FLT3 inhibitor efficacy in AML with FLT3-ITD is short-lived, frequently due to new mutations, most commonly in NRAS. Sphingosine kinase 1 (SPHK1), which phosphorylates sphingosine to generate sphingosine-1-phosphate (S1P), is upregulated and localized to the plasma membrane in RAS-mutated cells. We studied S1P and FLT3 co-targeting to overcome FLT3 inhibitor resistance in NRAS-mutated FLT3-ITD AML cells.
Efficient Ambient‐All‐Laser‐Annealed Wide Bandgap Perovskite Solar Cells
1 Introduction Wide bandgap (WBG) metal halide perovskites where the bandgap energy (Eg) >1.7 eV have attracted enormous research interest recently due to the ease of integration in multiple junction perovskite photovoltaic devices.[1, 2] In recent years, significant advancements have been made on various types of perovskite multi-junction tandems with wide bandgap (WBG) perovskite sub-cells directly deposited on top of Si, perovskite, copper indium gallium selenide, and organic photovoltaic...
Effects of sex and hydration status on kappa opioid receptor‐mediated diuresis in rats
CONFLICT OF INTEREST STATEMENT The authors have no conflict of interest to report. Supporting Information Filename Description bcpt14008-sup-0001-Supplementary_Material.docxWord 2007 document , 430.2 KB FIGURE S1: Effects of circulating oestrogen levels on the diuretic effects of U50488 in normally hydrated female Wistar rats. Figure S2: Effects of circulating oestrogen levels on the diuretic effects of U50488 in water-loaded female Wistar rats. REFERENCES 1, , , .
Synthesis of Stable Isotope, Tritiated, and Carbon‐14 Labeled Balcinrenone
As part of a medicinal chemistry program aimed at discovering a mineralocorticoid receptor modulator for treatment of kidney and cardiovascular indications, multiple labeled versions of the lead compound, balcinrenone (AZD9977), were prepared. Four stable isotope labeled versions of the compound were prepared for clinical bioanalysis and biological investigations. Three of these stable isotope labeled compounds were tritiated as well as the parent for biology applications and DMPK investigations.
Inorganic‐Cation Pseudohalide 2D Cs2Pb(SCN)2Br2 Perovskite Single Crystal
Adv. Mater. 2022, 34, 2104782 DOI: 10.1002/adma.202104782 In this Correction, it is clarified that, contrary to the originally published article, CsPbBr3 is, in fact, present even in a freshly grown “non-degraded” Cs2Pb(SCN)2Br2 crystal as an impurity at a very small amount, <1% by volume, that can be detected optically but not by powder X-ray diffraction (pXRD), and its presence is throughout the crystal bulk.
Piperidine and Pyridine Series Lead-Free Dion-Jacobson Phase Tin Perovskite Single Crystals and Their Applications for Field-Effect Transistors
Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Nano 2024, XXXX, XXX CCDC 2202681, 2202682, 2202683, and 2202705 contain supplementary crystallographic data for this work. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif. Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions.
Influence of Organic Spacer Cation on Dark Excitons in 2D Perovskites
1 Introduction 2D perovskites have attracted significant attention in recent years due to their unique optoelectronic and structural properties.
5 ingredients to power sports nutrition formulations
According to Nutrition Business Journal, primary considerations for a first-time purchase amongst regular sports nutrition users include flavor, trust and effectiveness. For product development scientists, much of that reassurance that their next formulation will be effective for the end user stems from the incorporation of ingredients backed by human clinical trials. Consider these five ingredients in your next formulation.
Polydopamine as a visible‐light photosensitiser for photoinitiated polymerisation
Graphical Abstract Polydopamine free radicals are observed to be photo-responsive under visible light irradiation, amplifying semiquinone radical population and modifying redox potential. Using polydopamine nanoparticles, the researchers photo-initiate free-radical polymerization of vinylic monomers via sensitization of a diphenyliodonium photo-initiator. This work offers important insights into melanin-like materials and presents PDA as a promising photosensitizer.
Smartwatch-based prediction of single-stride and stride-to-stride gait outcomes using regression-based machine learning
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Understanding and Appreciating Burnout in Radiologists
1 C.R.B. and A.M.B. contributed equally to this article. References 1. Summers RF . The Elephant in the Room: What Burnout Is and What It Is Not . Am J Psychiatry 2020 ; 177 ( 10 ): 898 – 899 . Crossref, Medline, Google Scholar 2. Kane L . Physician Burnout & Depression Report 2022: Stress, Anxiety, and Anger . MEDSCAPE online . https://www.medscape.com/slideshow/2022-lifestyle-burnout-6014664 Accessed February 14, 2022 . Google Scholar 3. APA Wellbeing Ambassador Toolkit.
Percutaneous Sclerotherapy of a Large Trans-Spatial Oropharyngeal Venous Malformation Using Multimodality Guidance
A 37-year-old woman with a large, infiltrative face and neck venous malformation (VM) was treated with percutaneous sclerotherapy using combined ultrasound, fluoroscopy, and computed tomography (CT) guidance. No institutional review board approval was required for this case report. Symptoms included pain, swelling, difficulty in swallowing, and facial pressure.
Imaging Manifestations and Interventional Treatments for Hereditary Hemorrhagic Telangiectasia
1 A.R.K. and A.J.S. contributed equally to this work. Abstract Hereditary hemorrhagic telangiectasia is an autosomal dominant disorder that causes multisystem vascular malformations, and early diagnosis, screening, and multidisciplinary treatment are important to decrease complications and improve quality of life.
Fringe visibility errors resulting from dual object imaging for stellar interferometers
Abstract Practical stellar interferometry for space domain awareness is challenged by the relative motions of orbital objects and telescope arrays that require array phasing using guide stars. An orbital object’s image sensitivity to the location and brightness of the guide star is problematic, possibly resulting in a degraded resolution or loss of image content when both objects fall within the interferometer’s field of view.
Characteristics and Outcomes of Percutaneous Biliary Interventions in the United States
Abstract Objective To explore baseline characteristics, comorbidities, and clinical diagnoses in the prediction of outcomes for inpatient percutaneous biliary interventions in the United States. Methods Hospitalizations for percutaneous transhepatic cholangiography and percutaneous biliary drainage were studied using the National Inpatient Sample 2012 to 2015.
Weight Loss after Left Gastric Artery Embolization: A Systematic Review and Meta-Analysis
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 Flow chart showing study selection. RSNA = Radiological Society of North America. Figure 2 Forest plots showing effect sizes and the pooled results. Figure 3 Forest plots of the pooled results for absolute and percentage weight change after excluding each individual study.
A natural solution to photoprotection and isolation of the potent polyene antibiotic, marinomycin A
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Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein
Polyketides are secondary metabolites which display both valuable pharmaceutical and agrochemical properties. Biosynthesis is performed by polyketide synthases (PKSs), and the acyl carrier protein (ACP), a small acidic protein, that transports the growing polyketide chain and is essential for activity. Here we report the synthesis of two aromatic probes and a linear octaketide mimic that have been tethered to actinorhodin ACP.
Groups relationships - Detailed or Direct?
Then I have a Model which have the and an associated. And finally I have a which tells all people that have access to that Item. So now a new feature must be added, which is Groups. So I thought about two aproaches and I would like to know which one is the more correct. So two things I'm clear, one is to add a new property to the Model.
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