Christopher Richard Parish on Muck Rack

Christopher Richard Parish

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Using rotational integration of oblique interferometric scattering to track axial spatiotemporal responses of tubular membrane protrusions

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By Junyu Liu, David J. Herrmann, Paul Timpson, Tri Giang Phan, Viviane Delghingaro-Augusto, Huafeng Liu, Min Guo, Woei Ming Lee, Christopher Richard Parish
| Nature Verified
Abstract The 3D spatiotemporal dynamics of tubular membrane protrusions are crucial for understanding phagocytosis, cellular communication and mechanobiology. Confocal microscopy, despite its prevalent use in membrane protrusion studies, presents limitations due to its inherently low axial resolution and high phototoxicity, which significantly hinder live imaging of tubular protrusion along the axial plane.
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