Christopher Starr
New York
As seen in:
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BioRxiv,
Cell Press,
Dove Medical Press,
Healio,
Healio Ophthalmology,
Modern Healthcare,
Citeline,
Ophthalmology Times,
Optometry Times
and
Ophthalmologist in New York City
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Articles by Christopher Starr
Corneal ulcers, fungal infections may occur after uneventful refractive surgery
Ask a clinical question and tap into Healio AI's knowledge base. Key takeaways: On stage at OSN New York, experts discussed several unique corneal cases. These cases included a fungal infection after PRK and a patient with decreased corneal sensation after LASIK. At OSN New York, Healio | OSN Cornea/External Disease Board Member Eric D. Donnenfeld, MD, and a panel of experts examined a series of unusual complications that occurred after routine refractive procedures.
Retinoid X Receptor as a Therapeutic Target to Treat Neurological Disorders Associated with alpha-Synucleinopathy
Abstract This study investigated the therapeutic potential of the nuclear retinoid X receptor (RXR) in mitigating the progression of a-synucleinopathies (aSNPs), particularly in Parkinson disease (PD). PD-like pathology in mice was successfully induced through the co-delivery of AAV expressing human a-synuclein (aS) and aS preformed fibrils (PFFs) into the substantia nigra pars compacta (SNpc).
Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Glucose-Sensing ChREBP Protein in the Pathogenesis of Diabetic Retinopathy
Abstract Glucose-sensing ChREBP and MondoA are transcriptional factors involved in lipogenic, inflammatory, and insulin signaling pathways implicated in metabolic disorders; however, limited ocular studies have been conducted on these proteins. We aimed to investigate the potential role of ChREBP in pathogenesis of diabetic retinopathy (DR). We used diabetic human and mouse retinal cryosections analyzed by immunohistochemistry. qRT-PCR was performed to quantify gene expression.
Retinoid X Receptor as a Novel Drug Target to Treat Neurological Disorders Associated with α-Synucleinopathies.
Abstract The pathology of Parkinson Disease (PD) is multifaceted, with chronic neuroinflammation associated with glial cell activation standing out as a hallmark of PD pathophysiology. While a few treatments exist to interfere with inflammation, a breakthrough therapy based on innovative molecular mechanisms and targets is still awaited.
Development of TRIB3-Based Therapy as a Gene-Independent Approach to Treat Retinal Degenerative Disorders
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Innovations in Ocular Surface Disease: What is the Impact of Lifestyle?
Innovations in Ocular Surface Disease: What is the Impact of Lifestyle? I. Paul Singh, MD; and Christopher E. Starr, MD Lifestyle is a broadly defined term comprising the influences of personal choices, environmental factors, and daily decisions. But how does all of that affect the health of the ocular surface? In this episode, Christopher E. Starr, MD, joins I. Paul Singh, MD, for an in-depth discussion about the global TFOS Lifestyle Workshop and its work to try and answer that question.
Comparative Proteomic Study of Retinal Ganglion Cells Undergoing Various Types of Cellular Stressors
Abstract Retinal ganglion cell (RGC) damage serves as a key indicator of various retinal degenerative diseases, including diabetic retinopathy (DR), glaucoma, retinal arterial and retinal vein occlusions, as well as inflammatory and traumatic optic neuropathies. Despite the growing body of data on the RGC proteomics associated with these conditions, there has been no dedicated study conducted to compare the molecular signaling pathways involved in the mechanism of neuronal cell death.
Reproxalap in Patients with Seasonal Allergic Conjunctivitis
Introduction Reproxalap, a novel chemical entity in late-stage clinical development for the treatment of ocular inflammation, chemically sequesters a class of small molecules known as reactive aldehyde species (RASP).
What Type of Practice Does One Choose?
THE FACTORS THAT WERE MOST IMPORTANT TO ME AS I PREPARED TO LEAVE MY FELLOWSHIP PROGRAM By Richard M. Awdeh, MD Joining an academic ophthalmic practice was one of the best and most gratifying decisions of my life. This article shares a few of the decisive points from my interview process in an effort to help current residents and fellows choose a practice. COLLEAGUES The most important question to ask yourself when selecting any job is who will be your colleagues?
VIDEO: Antidepressants do not have impact on dry eye nasal spray
Source/Disclosures Source: Healio Interviews Disclosures: Starr reports consulting for Oyster Point Pharma. We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. CHICAGO — In this Healio Video Perspective from Eyecelerator@AAO, Christopher E. Starr, MD, discusses post hoc data investigating Tyrvaya nasal spray for dry eye disease treatment in patients on antidepressants.
Understanding Dry Eye Flares and Their Causes
Understanding Dry Eye Flares and Their Causes Christopher E. Starr, MD; and Neda Shamie, MD Christopher E. Starr, MD, joins Neda Shamie, MD, to discuss a rapid evidence assessment of the characteristics of periodic flares of dry eye disease. Find out more about a phenomenon that is not well understood. To access the full review, please visit the link here: https://pubmed.ncbi.nlm.nih.gov/34303844/ Posted: 6/30/2022
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells
Ahn S. Olive M. Aggarwal S. Krylov D. Ginty D.D. Vinson C. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Mol. Cell. Biol. 1998; 18: 967-977 Almasieh M. Levin L.A. Neuroprotection in Glaucoma: Animal Models and Clinical Trials. Annu. Rev. Vis. Sci. 2017; 3: 91-120 Ashpole N.M. Hudmon A. Excitotoxic neuroprotection and vulnerability with CaMKII inhibition. Mol. Cell. Neurosci. 2011; 46: 720-730 Ashpole N.M. Song W. Brustovetsky T.
Dry Eye Awareness Month: Focus on these 3 Goals - Ophthalmology 360
By Christopher E. Starr, MD, FACS July is Dry Eye Awareness Month, when eye care practitioners at every level are reminded that although we’ve been learning and growing in our capacity to understand and treat ocular surface disease, there is still work to be done in helping the public perceive their symptoms as a treatable condition, rather than something “normal” that they need to endure. In July, patients will see outreach from their doctors, companies, and nonprofit organizations.
VIDEO: Retrospective study sheds light on nature of dry eye disease flares
May 02, 2021 1 min watch Save Source/Disclosures Published by: Source: Starr C, et al. Dry eye disease flares: A ten-year literature review. Presented at: Association for Research in Vision and Ophthalmology annual meeting; May 1-7, 2021 (virtual meeting). ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . We were unable to process your request. Please try again later.
Medicare cuts threaten the livelihood of academic health centers
Last month, the Centers for Medicare & Medicaid Services (CMS) proposed a rule that will cut Medicare payments for nearly all surgical procedures starting January 1, 2021. In some cases, surgeons will see up to 9% reductions in reimbursement for care. Cutting payments means less money for university medical centers like mine that fund critical clinical research, and now is hardly the time to be cutting money for medical research. Academic hospitals are the backbone of the medical community.
Gauge expected outcomes before conducting penetrating keratoplasty
In some cases, a primary keratoprosthesis may be the best choice. You've successfully added Ophthalmology: Cornea/External Disease to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Welcome to another edition of CEDARS/ASPENS Debates.
I need a van,trailer.storage to... by Christopher Starr
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