Christopher SY Benwell

Abstract As an alternative to the Diagnostic and Statistical Manual of Mental Disorders, transdiagnostic approaches that identify latent dimensions of psychopathology through factor analysis have gained prominence in recent years. A key critique of these approaches, however, is that they are performed at the level of symptoms only. This begs the question: are these dimensions truly more valid predictors of external outcomes than existing alternatives?

Abstract The mechanosensing properties of endothelial cell-cell junctions are essential for vascular beds to respond to the mechanical forces exerted by blood flow. In states of disturbed flow, endothelial cells (ECs) become activated and transition to a pro-inflammatory, atheroprone phenotype.

Abstract Research on brain-behaviour relationships often makes the implicit assumption that these derive from a co-variation of stochastic fluctuations in brain activity and performance across trials of an experiment. However, challenging this assumption, oscillatory brain activity, as well as indicators of performance, such as response speed, can show systematic trends with time on task.