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Chryslain Sumian

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Migration of di(2‐ethylhexyl) phthalate, diisononylcyclohexane‐1,2‐dicarboxylate and di(2‐ethylhexyl) terephthalate from transfusion medical devices in labile blood products: A comparative study

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By Emmanuel Chazard, Aurélie Thelliez, Macopharma Tourcoing France, Chryslain Sumian
| Wiley Online Library Verified
Abstract Background and Objectives Polyvinyl chloride (PVC) plasticized with di(2-ethylhexyl) phthalate (DEHP) is a widely used material for medical transfusion devices. Not covalently bound to PVC, DEHP can migrate into blood products during storage. Recognized as an endocrine disruptor and raising concerns about its potential carcinogenicity and reprotoxicity, DEHP is gradually being withdrawn from the medical device market.
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