Chrystel Marton on Muck Rack

Chrystel Marton

As seen in: Nature
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Articles

Securing raw materials, reagents, and consumable supplies in the academic bioproduction UNITC network: because the chain is only as strong as its weakest link | Bone Marrow Transplantation

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By Jeanne Galaine, Chrystel Marton, Guillaume Dachy, Boris Calmels, Christian Chabannon, Edouard Forcade, Sébastien Viel, John de Vos, Hélène Boucher, Marina Cavazzana, Jérémie Martinet, Olivier Boyer, Christophe Ferrand, Ibrahim Yakoub-Agha, Marina Deschamps
| Nature Verified
Abstract Academic autologous cell manufacturing offers key advantages, including cost-effectiveness, accessibility, and flexibility. However, the management of Raw Materials, Reagents, and Consumables (RMRCs) is essential for ensuring product purity, safety, and effectiveness. Variations in RMRC quality can increase production costs and result in batch failures.
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Harmonisation of quality control tests for academic production of CAR-T cells: a position paper from the WP-bioproduction of the UNITC consortium - Bone Marrow Transplantation

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By Guillaume Dachy, Christophe Ferrand, Jérémie Martinet, Christian Chabannon, John de Vos, Edouard Forcade, Sébastien Viel, Olivier Boyer, Chrystel Marton, Marine Deschamps
| Nature Verified
Abstract This position paper from the Bioproduction Working Group of the UNITC Consortium seeks to harmonize quality control (QC) procedures for academic production of autologous CAR-T cells. The primary objective is to standardize QC testing for batch release in academic cell therapy units. Academic CAR-T manufacturing under the hospital exemption pathway enables faster, more cost-effective production and the use of fresh cells, eliminating the need for cryopreservation.
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