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Chuankai Chen

As seen in: MDPI, ACS Publications, BioRxiv
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Articles

Down-Regulation of AKT Proteins Slows the Growth of Mutant-KRAS Pancreatic Tumors

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By Chuankai Chen, Ya-Ping Jiang, Inchul You, Nathanael S. Gray
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Down-regulation of AKT proteins slows the growth of mutant-KRAS pancreatic tumors

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By Ya-Ping Jiang, Inchul You, Nathanael S. Gray, Chuankai Chen
| BioRxiv
Abstract Serine/threonine kinase AKT isoforms play a well-established role in cell metabolism and growth. Most pancreatic adenocarcinoma (PDAC) harbors activation mutations of KRAS, which activates the PI3K/AKT signaling pathway. However, AKT inhibitors are not effective in the treatment of pancreatic cancer.
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Fluorinated 1,7-DO2A-Based Iron(II) Complexes as Sensitive 19F MRI Molecular Probes for Visualizing Renal Dysfunction in Living Mice

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By Lingxuan Li, Chuankai Chen, Yifan Bu, Junjie Wang
| ACS Publications
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