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Chun-Yu Yin

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Articles

Sucrose preference test for measurement of stress-induced anhedonia in mice

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By Meng-Ying Liu, Chun-Yu Yin, Li-Juan Zhu, Xian-Hui Zhu
| Nature Verified
Anhedonia is the inability to experience pleasure from rewarding or enjoyable activities and is a core symptom of depression in humans. Here, we describe a protocol for the measurement of anhedonia in mice, in which anhedonia is measured by a sucrose preference test (SPT) based on a two-bottle choice paradigm. A reduction in the sucrose preference ratio in experimental relative to control mice is indicative of anhedonia.
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