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Abstract Clear cell renal cell carcinoma (ccRCC) remains a lethal malignancy driven in part by SWI/SNF dysfunction, yet the mechanistic basis of this link is unclear. We identify SMARCD1, a core SWI/SNF subunit, as a tumor suppressor progressively silenced by DNMT3B-mediated promoter hypermethylation in ccRCC.
1 Introduction Approximately 70% of the Earth's surface is covered by water. As land resources continue to be consumed and increasing emphasis is placed on the protection of ocean rights and interests, the number of people engaged in marine-related activities has increased rapidly, resulting in a growing demand for underwater information transmission. Therefore, underwater wireless communication (UWC) technology has attracted increasing attention.
Exponentially enhanced photocatalytic alkane production from biomass-derived fatty acid decarboxylation via self-heating induced conformational inversion Heating is the most convenient means to enable unfavorable chemical reactions to scale application, but photocatalysis rarely uses it because its driving force has always been identified as the intensity of excitable light and the charge separation efficiency, which both are temperature-independent or even a negative correlation.
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