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Chunming Fei on Muck Rack

Chunming Fei

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Tegoprazan-based dual therapy versus bismuth-containing quadruple therapy for Helicobacter pylori eradication: a prospective, multicenter, open-label, non-inferiority, randomized controlled trial

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By Haocheng Wang, Yi Qu, Jun Wang, Jian Yao, Zhi Yang, Lu Shen, Xiaofeng Ye, Meijuan Xi, Minyi Xu, Jianxin Ge, Zhimei Zhang, Zhenyu Zhang, Chunming Fei
| Nature Verified
Abstract Background Current standard therapies for Helicobacter pylori (H. pylori) are limited by side effects and antibiotic resistance. Evidence suggests that high-dose amoxicillin dual therapy with a proton pump inhibitor offers comparable efficacy with an improved safety profile. Methods This trial substituted the novel acid blocker tegoprazan for a proton pump inhibitor in the dual therapy regimen. We enrolled 400 patients with confirmed H.
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