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Comparison of cerebral oxygen extraction fraction using ASE and TRUST methods in patients with sickle cell disease and healthy controls
Authors’ contributions Slim Fellah data processing, paper writing, statistical analysis, figures and tables (co-first author) Chunwei Ying data processing, paper writing, figures and tables (co-first author) Yan Wang paper revision, statistical analysis Kristin P. Guilliams paper revision, data interpretation Melanie E.
Examining temporal features of BOLD-based cerebrovascular reactivity in clinical populations
1. Introduction The cerebrovascular network is tightly regulated to maintain appropriate cerebral blood flow in the presence of systemic changes in blood pressure (1). Changes in blood pressure, neuronal activity, or arterial blood gases can elicit strong cerebrovascular responses and changes in vascular tone. Increasing the fraction of inhaled CO2 is a common cerebrovascular reactivity (CVR) challenge, as it increases the partial pressure of CO2 in arterial blood.
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