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Cierra Girardi on Muck Rack

Cierra Girardi

As seen in: BioRxiv
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Articles

Tryptophan and IFN-γ Differentially Modulate Cellular Uptake, Intracellular Trafficking, and Gene Expression of Messenger RNA-Loaded Lipid Nanoparticles in Dendritic Cells

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By Nikki Crowley, Zitao Ma, Reena Jatyan, Cierra Girardi
| BioRxiv
Abstract Lipid nanoparticle (LNP)-mediated mRNA delivery has emerged as a powerful platform for both immunostimulatory and immunomodulatory applications. However, the influence of local immunometabolic cues on the intracellular fate and translational efficiency of mRNA-LNPs remains poorly understood.
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