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Cindy Pino on Muck Rack

Cindy Pino

As seen in: Nature, BioRxiv

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Articles

Linkage of nucleotide and functional diversity varies across gut bacteria.

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By Byron Smith, Veronika Dubinkina, Chunyu Zhao, Cindy Pino
| BioRxiv
Abstract Understanding the forces shaping genomic diversity within bacterial species is essential for interpreting microbiome evolution, ecology, and host associations. Here, we analyze over one hundred prevalent gut bacterial species using the Unified Human Gut Genome (UHGG) collection to characterize patterns of intra-specific genomic variability.
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Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages - Nature Communications

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By Dounia Le Guillou, Cindy Pino, Jacquelyn J. Maher, Edward Hsiao, Marko Groeger
| Nature Verified
Abstract Hepatic insulin resistance is recognized as a driver of type 2 diabetes and fatty liver disease but specific therapies are lacking. Here we explore the potential of human induced pluripotent stem cells (iPSCs) for modeling hepatic insulin resistance in vitro, with a focus on resolving the controversy about the impact of inflammation in the absence of steatosis.
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