Cíntia Marques Coelho

You are already at the latest version The mevalonate pathway (MVA) is a central metabolic route responsible for the biosynthesis of isoprenoids, a vast and diverse class of biomolecules essential for cellular structure, signaling, and physiology. This review provides a comprehensive overview of the MVA pathway, addressing its distribution in different domains of life, evolutionary origins, and overall organization.

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Abstract : The use of nucleotides for biomedical applications is an old desire in the scientific community. As we will present here, there are references published over the past 40 years with this intended use. The main problem is that, as unstable molecules, nucleotides require some additional protection to extend their shelf life in the biological environment.