Clay Douglas Rouse on Muck Rack

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Articles

ABL Kinases Modulate EZH2 Phosphorylation and Signaling in Metastatic Triple Negative Breast Cancer

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By Tatiana M. Prioleau, Clay Douglas Rouse, Ann Marie Pendergast, Ashley Colemon
| biorxiv.org
Abstract Triple-negative breast cancer (TNBC) remains a leading cause of cancer associated deaths in women owing to its highly metastatic potential and limited treatment options. Recent studies have shown that expression of proteins associated with epigenetic regulation of gene expression are associated with metastatic relapse, however targeting epigenetic regulatory proteins has not resulted in effective therapies for TNBC in the clinic.
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Regulation of Age-Related Lipid Metabolism in Ovarian Cancer

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By Jihua Feng, Olivia Byrd, Clay Douglas Rouse, Isabella Coogan
| biorxiv.org
Abstract Although a lot of effort has been dedicated to ovarian cancer (OC) research, the mortality rate is still among the highest in female gynecologic malignancies. The effects of the aged tumor microenvironment are still being undermined despite age being the highest risk factor in ovarian cancer development and progression.
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