Skip To Main Content
Colin WG Fishwick on Muck Rack

Colin WG Fishwick

As seen in: BioRxiv
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Colin WG

Contact Colin WG, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Using site-directed mutagenesis to further the understanding of insulin receptor-insulin like growth factor-1 receptor heterodimer structure.

|
By Stephen P. Muench, Tarik ISSAD, Samuel J Turvey, Colin WG Fishwick
| BioRxiv
Abstract Type 2 diabetes is characterised by the disruption of insulin and insulin-like growth factor (IGF) signalling. The key hubs of these signalling cascades; the Insulin receptor (IR) and Insulin-like growth factor 1 receptor (IGF1R) are known to form functional IR-IGF1R hybrid receptors which are insulin resistant. However, the mechanisms underpinning IR-IGF1R hybrid formation are not fully understood, hindering the ability to modulate this for future therapies targeting this receptor.
Open in Who Shared Issue with article?
See all 1 articles