Conception de Médicaments

1 Introduction Favelines are a class of diterpenes with a benzocycloheptene core (Figure 1), predominantly found in Cnidoscolus quercifolius, and whose biosynthetic pathway is still unknown. Popularly known as favela or faveleira, C. quercifolius is a medicinal plant from the Caatinga biome, located in the semiarid region of Brazil [1]. This biome covers about 10% of the Brazilian territory, mainly concentrated in the Northeast region. In contrast to the typically dry vegetation of the Caatinga, C.