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Công ty Cống

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Articles

Flexible and scalable federated learning with deep feature prompts for digital pathology

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By Cong Cong, Công ty Cống, Antonio Di Ieva, Angela Chou, Anthony Gill, Enrico Coiera, Sidong Liu
| Nature Verified
Abstract Collaborative learning across medical institutions is essential for building robust and generalisable digital pathology models. Federated learning (FL) enables collaboration without centralising data, yet its adoption is limited by high communication costs, model heterogeneity, and privacy concerns. We propose Federated Deep Feature Prompting (FedDFP), an efficient FL framework tailored for heterogeneous clinical environments.
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Hepatokine ORM2 suppresses pathological ferritinophagy to prevent acute tissue injury

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By Hongyi Tang, Shu Wang, Fang Liu, Feng Jiang, Nan Yang, Rulin Zhang, Dongge Xia, Cong Cong, Công ty Cống, Yan Lu, Jie Yang, Jun Wu, Bing Zhou, Xuxu Sun, Boqian Shen, Xinyuan Xiong, Huiqin Zhu
| Nature Verified
Abstract Acute tissue injuries trigger rapid cellular damage, but cell-intrinsic protective programs attenuate pathology through regulatory axes. Here, we demonstrate that Orosomucoid 2 (ORM2), a hepatokine, is significantly upregulated during drug-induced acute liver injury. Knock out Orm2 exacerbates liver damage, while its overexpression provides protection, identifying ORM2 as an endogenous hepatoprotective factor during acute liver injury.
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The Impact of Omega-3 Fatty Acids on Triglyceride Levels in Patients w

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By Cong Cong, Công ty Cống, Xiaolan Zhang, Xiaoxia Zhang
| Dove Medical Press
Introduction The growing yearly prevalence of Metabolic Dysfunction–non-alcoholic fatty liver disease (MASLD) has emerged as a worldwide public health concern, driven by improved living conditions, evolving lifestyle habits, and the widespread occurrence of obesity, diabetes, and metabolic syndrome.1 Metabolic dysfunction-associated fatty liver disease (MASLD)—the term newly established by international consensus to replace previous designations including NAFLD and MAFLD—represents a major...
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