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Constance Harris

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Articles

Algal Toxin Goniodomin A Binds Potassium Ion Selectively to Yield a Conformationally Altered Complex with Potential Biological Consequences

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By Nathan D. Schley, Constance Harris, Craig J. Tainter, Donald F. Stec
| ACS Publications
The marine toxin goniodomin A (GDA) is a polycyclic macrolide containing a spiroacetal and three cyclic ethers as part of the macrocycle backbone. GDA is produced by three species of the Alexandrium genus of dinoflagellates, blooms of which are associated with “red tides”, which are widely dispersed and can cause significant harm to marine life.
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