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Costel C Darie on Muck Rack

Costel C Darie

As seen in: MDPI, ACS Publications, BioRxiv
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Articles

pH-Driven Enzymatic Breakdown and Release of Catalase from Alginate Hydrogel

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By Anna Tverdokhlebova, Ilya Sterin, Taniya Jayaweera, Costel C Darie
| ACS Publications
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pH-Driven Enzymatic Breakdown and Release of Catalase from Alginate Hydrogel

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By Anna Tverdokhlebova, Ilya Sterin, Taniya Jayaweera, Costel C Darie
| dx.doi.org
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Identification of Phosphotyrosine-Mutant Desmin in Human Pancreatic Cancer

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By Nancy Kendrick, Costel C Darie, Matthew C Hoelter, Andrew A Koll
| BioRxiv
Abstract Pancreatic ductal adenocarcinoma (PDAC), a deadly cancer with a 5-year survival rate of ~12%, is characterized by frequently mutated KRAS, early metastasis, and extensive desmoplasia. The latter, a formation of dense fibrotic tissue generated by pancreatic stellar cells (PSC) and tumor cells, makes up to 80% of the tumor mass and often leads to treatment failure.
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