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Articles by Laura Cooney
Autologous Hematopoietic Transplantation Reduces Brain Inflammatory and Axoglial Damage Biomarkers in Multiple Sclerosis
Information & Authors Published In Neurology® Neuroimmunology & Neuroinflammation Volume 13 • Number 6 • November 2026 : e200653 Publication History Received: April 1, 2026 Accepted: August 14, 2026 Published online: September 28, 2026 Published in issue: November 2026 Permissions Request permissions for this article. Data Availability All data will be publicly available from the Immune Tolerance Network TrialShare website. Disclosure L.A. Cooney, N.
IL-2 mutein selectively expands thymic memory Tregs with increased transendocytosis activity in healthy participants
ResearchClinical ResearchImmunology Open Access | 10.1172/jci.insight.193744 JCI Insight. https://doi.org/10.1172/jci.insight.193744. Copyright © 2026, Cooney et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Tregs play an essential role in immune tolerance, and Treg-promoting therapies are in development for the treatment of many inflammatory disorders.
Interview: Randy Houser talks music, acting and which song he is most proud of writing
Since releasing his first single in 2008, Mississippi native Randy Houser has become one of the biggest names in country music, racking up six studio albums – most recently 2022’s ‘Note To Self’ which was followed by a deluxe edition last year – and a string of hit singles including three number ones.
Abatacept Reduces CD319+ (SLAMF7) Cytotoxic T Cells and Cytokine Production in Systemic Sclerosis
Supporting Information Filename Description art70301-sup-0001-Disclosureform.pdfPDF document, 841.8 KB Disclosure Form art70301-sup-0002-Supinfo.docxWord 2007 document , 4 MB Data S1: Supporting Information
Review: Morgan Wade gets raw, rocky and romantic on 'Obsessed'
Morgan Wade has been forging a unique path for herself in the country music world since she released her debut single, ‘Wilder Days', back in 2021. The track catapulted Wade's first album ‘Reckless' to the top of Rolling Stone's Best Country Albums of the Year list and hit the top 30 on the charts, as well as seeing her win over a slew of fans and sell out shows on both her UK headline tours in 2022 and 2023.
Interview: Colin Stough on 'Lookin' For Home', 'American Idol' and what's next
He may still be only 19 but Colin Stough has already been making a big name for himself in the world of country music. After placing third on season 21 of American Idol last year, where he won over fans with his gravelly vocals and country-rock sound, the Mississippi native released his debut EP ‘Promiseland', racked up over 19 million global streams and has opened for artists including Kidd G, Chase Matthew and Drake White.
Interview: Lindsay Ell on working with Shania Twain, UK fans and plans for new music
2023 was a stellar year for Lindsay Ell – and so far 2024 is shaping up in similar fashion. After making her C2C main stage debut last March, the singer-songwriter – beloved among UK fans for her heartfelt, honest lyrics and incredible guitar skills – also picked up a Canadian Country Music Award and was nominated for a Canadian Screen Award as host of Canada's Got Talent, as well as working alongside Maren Morris, Zac Brown Band and HARDY.
Interview: Tigirlily Gold talk 'Blonde' reaction, ACM Awards win and what's next
Since making their UK debut at C2C just two years ago, siblings Kendra and Krista – better known as Tigirlily Gold – have become beloved by the country community here. Known for their sassy yet emotionally rich songwriting and warm, engaging stage presence, the pair have since been back across the pond earlier this year where they played the C2C Spotlight Stage, as well as scoring their first Top 40 hit with ‘I Tried A Ring On'.
Interview: Kyle Daniel on 'Kentucky Gold', playing The Long Road and more
It's no secret that Kyle Daniel has an ongoing love affair with UK country fans – ever since he made his debut here in 2019, we've been welcoming him back with open arms. With a slew of festivals under his belt including Nashville Meets London and The Long Road (where he'll be performing again in just a few weeks), he's gained critical acclaim and won over audiences with his country-rock sound and warm, infectious personality.
Interview: Lindsay Ell on working with Shania Twain, UK fans and plans for new music
Laura has been writing for Entertainment Focus since 2016, mainly covering music (particularly country and pop) and television, and is based in South West London.
Disordered eating more common in PCOS, regardless of body weight
Read more You've successfully added Polycystic Ovary Syndrome to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Key takeaways: Women with polycystic ovary syndrome are at greater risk for developing any form of disordered eating. Risk for disordered eating was high independent of BMI.
Interview: Emily Ann Roberts on 'Can't Hide Country', CMA Fest, touring with Blake Shelton and more
East Tennessee native Emily Ann Roberts first shot to fame when she appeared on The Voice back in 2015, whilst she was still in high school. She finished in second place and since then has gone on to gain critical acclaim for her soaring vocals, traditional country sound and honest, heartfelt songwriting with a dash of humour.
Review: Gavin Adcock rocks out and gets reflective on 'Actin' Up Again'
Originally from Watkinsville, Georgia, Gavin Adcock began writing songs in high school but didn't make the switch into music until 2021, after a key injury put paid to his football career. Since then he's racked up over 100 million streams worldwide and played a string of sold-out headline shows, and now he's releasing his second album ‘Actin' Up Again', the follow-up to last year's ‘Bonfire Blackout'.
Review: Tigirlily Gold's 'Blonde' is charming and confident with fun 90s touches
Sisters Kendra and Krista Slaubaugh – better known as Tigirlily Gold – started their band in high school back in North Dakota before moving to Nashville, where they regularly performed at local bars ahead of their big break. They released their self-titled debut EP in 2021, have toured with the likes of Walker Hayes and Ashley McBryde, and performed at C2C two years on the trot (including making their Spotlight Stage debut this March).
Review: Avery Anna digs deep on open and vulnerable 'Breakup Over Breakfast'
Despite being just 20 years old, Avery Anna has already racked up some serious success, with nearly 350 million global streams and opening for artists including BRELAND and Jordan Davis as well as heading out on her own headline tour and performing at C2C. After breaking through with her viral hit ‘Narcissist' in 2021 – which was later featured on her debut EP ‘Mood Swings' – now she's back with her first full length album, ‘Breakup Over Breakfast'.
Review: Kyle Daniel delivers testament to the power of perseverance on 'Kentucky Gold'
It's safe to say that ever since he made his UK debut back in 2019, Kyle Daniel has become one of the most beloved acts among UK country fans – and the feeling is very much mutual. He's been a frequent visitor here, performing at the likes of Nashville Meets London and The Long Road (where he'll be performing again later this summer), and genuinely loves chatting to fans whether that's in person or on social media.
Colin Stough rocks out on punchy sophomore EP 'Lookin' For Home'
He might be only 19 but Mississippi native Colin Stough is already making big waves on the country music scene. After finishing third on American Idol in 2022, he's racked up almost 20 million global streams and opened for artists like Chase Matthews, Kidd G and Drake White. Now he's releasing his sophomore EP ‘Lookin' For Home', the follow-up to 2023's ‘Promiseland'.
Interview: Alana Springsteen on playing BST Hyde Park, 'Nashville Sessions' EP and new music
Since she made her UK debut last year at C2C, Alana Springsteen has become one of the most popular rising country stars with audiences here. Blending country, pop and rock influences alongside raw and honest lyrics, she's since played The Long Road and supported Eli Young Band on tour here, as well as returning to C2C this March for her first London headline show and co-hosting the main stage alongside the legendary Bob Harris. Last week she was back once more to perform at BST Hyde Park.
BST Hyde Park roundup: The Corrs, Anne-Marie, Elle King and more
BST Hyde Park is in full swing once again, with a line-up packed full of stars from every genre of music. This year's headliners so far have included Morgan Wallen, Shania Twain, SZA, Kings Of Leon, Robbie Williams and Andrea Bocelli – with Stevie Nicks, Kylie Minogue and Stray Kids still to come. But even further down the bill there's still a slew of incredible artists playing on the main Great Oak Stage as well as smaller stages around the site.
Shania Twain, BST Hyde Park, London live review
Over the past three decades, Shania Twain has played a huge role in many UK country fans' lives. Breaking through with her second album ‘The Woman In Me' back in 1995, she followed that up with ‘Come On Over', which has sold over 40 million copies worldwide. Since then she's racked up five Grammy Awards (among many other trophies), two Las Vegas residences and three more studio albums, as well as countless tours around the world including her Queen Of Me tour which hit the UK last year.
Zandi Holup, BST Hyde Park, London live review
Pennsylvania-born Zandi Holup has been carving out a niche for herself in country music with her folk-influenced, singer-songwriter style and raw, honest writing. She signed with Big Loud Records and released her debut single ‘Gas Station Flowers' last year, and made her UK debut in March with an acoustic set at C2C festival. Yesterday she returned to the UK as part of the lineup for BST Hyde Park, opening the day with her performance on the Rainbow Stage.
Alana Springsteen, BST Hyde Park, London live review
Virginia Beach native Alana Springsteen first picked up a guitar aged seven and began writing songs when she was just nine years old. Since then she's grown into an artist who's beloved by fans in the US and UK for her heartfelt, powerful songs and energetic stage performances. She released her debut album, ‘TWENTY SOMETHING', last year and has been a frequent visitor to these shores, most recently joining Bob Harris as co-host for this year's C2C festival.
Morgan Wallen, BST Hyde Park, London live review
Morgan Wallen has rapidly established himself as the leading star of modern country music, and that doesn't look like it's going to change any time soon. With 11 number one singles and three albums under his belt, he's continuing to win over audiences on both sides of the pond as part of his One Night At A Time tour.
Top 10 Morgan Wallen songs we want to hear at BST Hyde Park
We're less than a week away from Morgan Wallen headlining at BST Hyde Park and anticipation is building rapidly. After his sell-out UK debut at The O2 in London last December, the country superstar will be back on this side of the pond for his biggest show yet, leading a star-studded lineup including Riley Green, ERNEST and Ella Langley.
Review: Halle Kearns shows versatility and songwriting skills on 'Quarter Life Crisis'
Missouri native Halle Kearns first came to many country fans' attention with her debut EP, ‘Finally', released in 2020. Since then she's racked up over 11 million TikTok views, 21 million global streams and over 80,000 Instagram followers. After performing at CMA Fest earlier this month, now she's back with her third project, ‘Quarter Life Crisis', the follow-up to her 2022 EP ‘Every Girl'.
Interview: Riley Green talks BST Hyde Park, 'Way Out Here' EP and what's next in 2024
Since he burst onto the scene with his debut single ‘There Was This Girl' back in 2019, Riley Green has been carving out a path for himself as part of the new wave of country stars. With strong neotraditional influences to his sound, he's already scored two top 15 albums – ‘Different ‘Round Here' and 2023's ‘Ain't My Last Rodeo' – as well as two top 5 singles, and won over a slew of fans in the process.
Taylor Swift The Eras Tour, Anfield, Liverpool live review
Where do we even begin to talk about the musical juggernaut that is Taylor Swift? She’s Spotify’s most streamed artist, the highest-grossing touring female act and the reigning Time Person of the Year, with over 200 million record sales and a string of awards to her name, including four Album of the Year Grammys.
Review: CMA Fest Sunday: HARDY, Bailey Zimmerman, Carly Pearce and more
CMA Fest is drawing to a close for another year, but not before going out with a bang in the final Nissan Stadium show of the 2024 event. Every June, CMA Fest takes over Nashville, drawing tens of thousands of country music fans from around the globe.
Review: CMA Fest Friday: Luke Bryan, Cody Johnson, Kelsea Ballerini and more
CMA Fest is in full swing in Nashville, Tennessee, and after a fantastic start on Thursday, last night we were back in Nissan Stadium for the second of this week’s four nightly shows. For those who don’t know, every June, CMA Fest takes over Music City, drawing tens of thousands of country music fans from across the globe to the heart of Music City.
Review: CMA Fest Thursday: Thomas Rhett, Ashley McBryde, Jordan Davis and more
Every June, CMA Fest takes over Nashville, drawing tens of thousands of country music fans from across the globe to the heart of Music City. Now in its 51st year, the four-day extravaganza showcases 300 acts across multiple stages -from the genre’s biggest stars to up-and-coming artists – spread across the bustling streets of downtown Nashville to historic Ryman Auditorium and the state-of-the-art Nissan Stadium.
CMA Fest: 5 'can't miss' artists in Nashville on Saturday 8th June
Congratulations, you’ve made it to day three of CMA Fest 2024! By now the festival is in full swing and the streets of Nashville are hopping (even more so than usual) with some fantastic live music. Even if you don’t have tickets for the evening shows at Nissan Stadium, there are still plenty of artists to see for free on the stages downtown, with something for everyone to enjoy. It can be overwhelming to make sense of it all though, so we’ve done the hard work for you.
Interview: Josh Ross on UK fans, 'New Me' and what's next
2024 is shaping up to be a stellar year for Josh Ross. After the success of his 2023 single ‘Trouble’, the Canadian-born singer-songwriter signed with Universal Music Group Nashville as well as touring with the likes of Nickelback and Bailey Zimmerman and scooping the Canadian Country Music Awards Breakthrough Artist of the Year.
Kameron Marlowe gets vulnerable on rock-tinged new album 'Keepin' The Lights On'
North Carolina native Kameron Marlowe first rose to fame after his YouTube videos were spotted by a talent recruiter for The Voice. He made it to the Top 24 on the show before moving to Nashville to start his songwriting career, and released his debut single ‘Giving You Up’ in 2019. Now, after several successful tours – and a trip to the UK last year for C2C – he’s released his sophomore album ‘Keepin’ The Lights On’, the follow-up to 2020’s ‘We Were Cowboys’.
Interview: Redferrin on 'Old No. 7' EP, playing at C2C and what's coming next
Blake Redferrin – better known by his last name – started out as a dirt bike rider before branching out into songwriting, with cuts for artists including Florida Georgia Line and Nelly. However, it was the viral success of his song ‘Jack And Diet Coke’ which propelled him into the mainstream as an artist in his own right and saw him release his first EP ‘Old No. 7’ in February this year.
Highways Festival, London, live review
After making its debut last year with a triumphant headlining set from Kip Moore, this weekend Highways festival returned to London’s Royal Albert Hall on an ever bigger scale. Now spanning two days and a slew of extra activities (including Late Night Sessions with UK country stars Kezia Gill and Remember Monday and the sold-out Songwriters Round), the eight artists performing on the main stage came from all aspects of the country genre and showed just how diverse a style it really is.
Laci Kaye Booth shows honest and vulnerable side on 'The Loneliest Girl In The World'
Originally from Livingston, Texas, Laci Kaye Booth began performing live when she was just eight years old, but rocketed to fame when she auditioned for American Idol in 2018. After reaching the top five on season 17 of the show, she released her self-titled major label debut album in 2021. After being named one of CMT’s Next Women Of Country in 2022, now she’s back with the follow-up, ‘The Loneliest Girl In The World’.
Interview: Cheryl Baker on Eurovision memories, what she'd tell Olly Alexander and more
Eurovision 2024 is just around the corner, with Olly Alexander due to represent the UK in tomorrow’s Grand Final in Malmo with his song ‘Dizzy’. He’ll be following in the footsteps of many Eurovision legends – including Cheryl Baker, who won the contest as part of Bucks Fizz back in 1981 with ‘Making Your Mind Up’ (and gave us the now-legendary ‘skirt rip’ moment in the process!).
Lily Rose delivers punchy, powerful mission statement on 'Runnin' Outta Time'
Atlanta-born Lily Rose first shot to fame when her song ‘Villain’ went viral on TikTok back in 2020. Since then she’s toured alongside the likes of Shania Twain and Sam Hunt, performed on The Voice and Good Morning America, been nominated for the ACM Award for Best New Female Artist and scooped GLAAD’s Outstanding Breakthrough Artist Award in 2022.
Interview: Lily Rose talks new EP 'Runnin' Outta Time', playing at C2C and what's next
Since she first arrived on the country music scene with her TikTok smash hit ‘Villain’ in 2020, Lily Rose’s career has continued to blossom (if you’ll pardon the pun). She was named as one of the CMT Next Women of Country Class of 2022 and nominated for the ACM Award for New Female Artist of the Year the same year. Alongside these accolades, she’s toured with the likes of Shania Twain, Dylan Scott and Chris Lane, as well as recently opening up for Sam Hunt on the latest run of his Outskirts Tour.
Charley Crockett, Hoxton Hall, London live review
Texas native Charley Crockett has become one of the most beloved – and prolific – country artists around since he released his first album back in 2015. With a further 11 records under his belt, he’s become well known for his blend of country, blues and soul, as well as his outstanding live performances. To celebrate the release of his latest album ‘$10 Cowboy’ last month, this week he’s playing a run of three intimate shows at Hoxton Hall in London.
LeAnn Rimes, The O2 Arena, London live review
Where do we begin to talk about LeAnn Rimes? Since she burst into the music business at the age of just 13, she’s racked up over 48 million record sales worldwide – as well as nine top ten singles in the US – starred in a string of movies and scooped three ACM Awards and two Grammys.
Darius Rucker, Eventim Hammersmith Apollo, London live review
Darius Rucker has been one of the most popular artists among UK country fans ever since the release of his 2008 album ‘Learn To Live’. Since then he’s racked up a further six studio albums – most recently ‘Carolyn’s Boy’, released last year and named in tribute to his late mother – as well as scoring nine Country Airplay chart number one singles and performing around the world.
Interview: Marcus & Martinus on Eurovision, UK fans and what's next Original
Identical twins Marcus and Martinus first burst onto the music scene when they won Melodi Grand Prix Junior in their native Norway back in 2012.
Review: Tenille Arts takes us on an emotional rollercoaster with new album 'to be honest'
Originally from Saskatchewan in Canada, Tenille Arts first picked up a guitar when she was just 13 before finding her big break in 2019 when she performed her song ‘I Hate This’ on ‘The Bachelor’ in 2018. Since then she’s racked up over 8 million streams, won acclaim from the likes of Billboard Country Update, CMT and Rolling Stone, and released three studio albums, as well as regularly touring in the US, Canada and the UK.
Jon Pardi, O2 Shepherd's Bush Empire, London live review
Jon Pardi has become one of the leading lights of the neo-traditional revival in modern country since he broke through with ‘Head Over Boots’, from his 2016 sophomore LP ‘California Sunrise’ (named after his home state). Since then he’s racked up six number one singles on the Billboard Country Airplay chart and two more studio albums, most recently 2023’s ‘Merry Christmas From Jon Pardi’, as well as becoming a member of the Grand Ole Opry.
Review: Mackenzie Porter delivers pop-country with surprising depth on 'Nobody's Born With A Broken Heart'
Originally from Medicine Hat, Canada, MacKenzie Porter started out as an actress before moving into country music. She’s topped the Canada Country charts four times, as well as having a Billboard Country number one hit with her Dustin Lynch collaboration ‘Thinkin’ ‘Bout You’. Now she’s released her major label debut album, ‘Nobody’s Born With A Broken Heart’. The 19-track record opens with ‘Easy To Miss’, which sees Porter reminiscing on a breakup and not being quite able to let go yet.
Review: Charley Crockett skilfully treads the line between darkness and light on '$10 Cowboy'
Texas-born Charley Crockett has had a prolific career since releasing his debut album ‘A Stolen Jewel’ in 2015. With a further 11 records under his belt – most recently 2022’s critically acclaimed ‘The Man From Waco’, which saw him nominated for four trophies at the 2023 Americana Music Awards – he’s become beloved by fans for his blend of country, blues and Americana as well as his live performances. Now he’s back with the follow-up, ‘$10 Cowboy’, released today.
Interview: Mackenzie Porter on 'Nobody's Born With A Broken Heart', C2C memories and 2024 plans
It’s only April but 2024 is already shaping up to be a milestone year for Mackenzie Porter. Alongside performing at the Grand Ole Opry and being announced as host of the 2024 Canadian Country Music Awards, she’s been working on her debut album, ‘Nobody’s Born With A Broken Heart’, due for release this Friday. She also became a mum last month when she and her husband, fellow musician Jake Etheridge, welcomed their daughter Bowen.
Lainey Wilson, O2 Forum Kentish Town, London live review
In her own words, it’s safe to say that in the year since her last tripto the UK, Lainey Wilson’s life has become something of a whirlwind. After her triumphant performance at C2C festival last year, she’s toured the world, scooped the Best Country Album Grammy for her 2022 release ‘Bell Bottom Country’ and picked up five CMA Awards at last November’s ceremony, including the coveted Entertainer of the Year trophy.
Tyler Hubbard shows experimental side and songwriting skills on 'Strong'
Tyler Hubbard may still be best known to many country fans as half of superstar duo Florida Georgia Line, but in recent years he’s been carving out a new direction for himself as a solo artist. He released his debut self-titled solo album last year, which featured chart-topping singles ‘5 Foot 9’ and ‘Dancin’ In The Country’, and has been winning over fans with his live shows both on his own and supporting the likes of Kane Brown.
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