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Sa1459 BRUSH BORDER PROTEIN AND ULTRASTRUCTURAL ABNORMALITIES IN PEDIATRIC CROHN’S DISEASE PATIENTS
Also available on ScienceDirect
Editorial: Baseline Drug Clearance Predicts Outcomes in Children With Inflammatory Bowel Disease Treated With Vedolizumab
The pharmacokinetics of IBD biologics in children differ from adults. Differences are thought to be related to physiological (e.g., differences in body surface area and a higher rate of hypoalbuminemia), developmental (immature immune processing and higher prevalence of anti-drug antibody formation) and disease-related (e.g., severity and extent of inflammation) factors [1, 2].
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