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Dynamics and Molecular Interactions of GPI-Anchored CD59

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By Voisin TB, Couves EC, Tate EW
| nlm.nih.gov
Full text links Cite Display options Display options Format AbstractPubMedPMID Abstract CD59 is a GPI-anchored cell surface receptor that serves as a gatekeeper to controlling pore formation. It is the only membrane-bound inhibitor of the complement membrane attack complex (MAC), an immune pore that can damage human cells. While CD59 blocks MAC pores, the receptor is co-opted by bacterial pore-forming proteins to target human cells.
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