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Global, regional, and national burden trends of lip and oral cavity cancer among individuals aged 60 and above from 1990 to 2021: a systematic analysis based on the 2021 global burden of disease data | BMC Cancer | Full Text
Compared to 1990, the ASIR of LOCC in the elderly globally in 2021 was 23.13 per 100,000, representing an increase of 17.65%; ASPR was 72.19 per 100,000, rising by 32.68%; ASMR was 12.57 per 100,000, showing a 2.11% increase; and ASDR was 253.10 per 100,000 person-years, with a 0.64% increase. Based on these estimates, in 2021, there were 249,668.20 new cases of LOCC in the elderly, 789,771.00 prevalent cases, 134,429.65 deaths, and a loss of 2,762,875.97 health years.
A novel ceRNA regulatory network involving the long noncoding NEAT1, miRNA-466f-3p and its mRNA target in osteoblast autophagy and osteoporosis - Journal of Molecular Medicine
Abstract Osteoporosis (OP) is a systemic metabolic disorder characterized by a reduction in bone tissue volume. LncRNAs have been reported to act as regulators of several human diseases. Specifically, lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1) is involved in proliferation, differentiation and apoptosis in osteoclasts and bone marrow mesenchymal stem cells and regulates the occurrence and development of OP.
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