Cuneyd Yavas

Abstract Bromelain is a proteolytic enzyme complex naturally found in the stem, fruit, and juice of pineapple, while papain is a proteolytic enzyme derived from the latex of the papaya plant. These bioactive components have attracted increasing scientific interest due to their reported roles in cell proliferation and wound healing, suppression of oxidative stress through free radical scavenging, and apoptosis-related pathways.

Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References , , , , and . 2016. “Liver Glucose Metabolism in Humans.” Bioscience Reports 36, no. 6: e00416. https://doi.org/10.1042/BSR20160385. , , and . 2007.

1 Introduction Inherited retinal disorders (IRDs) represent a significant contributor to vision loss, constituting a diverse spectrum of retinal illnesses characterized by the degradation of photoreceptors. These disorders, affecting children and young individuals, primarily cause vision impairment worldwide [1]. Often presenting with ocular characteristics, IRDs encompass a genetically complex landscape, with approximately 250 causal genes associated with various clinical manifestations [2].