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Cunyu Tang on Muck Rack

Cunyu Tang

As seen in: Frontiers in Immunology
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Articles

Risk stratification and multi-omics reveal RAD51 inhibition as a radiosensitizing strategy in triple-negative breast cancer

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By Ran An, Jianming Li, Tianhui Liu, Hong Lu, Cunyu Tang
| Frontiers in Immunology
Abstract Background: Triple-negative breast cancer (TNBC) is a highly aggressive subtype characterized by significant inter- and intra-tumoral heterogeneity. Its varied response to radiotherapy limits clinical outcomes, yet the underlying molecular determinants remain poorly understood. Methods: By integrating single-cell and bulk transcriptomic data, we profiled cell-type-specific radiosensitivity and defined distinct molecular subtypes via consensus clustering.
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