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Cyrielle Bories on Muck Rack

Cyrielle Bories

As seen in: Nature, Science Magazine
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Articles

Follicular regulatory T cells promote experimental autoimmune encephalomyelitis by supporting B cell egress from germinal centers

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By Fanny Martínez Verified, Julien Novarino, Cyrielle Bories, Coline Cotineau
| Science Magazine Verified
Editor’s summary Follicular regulatory T cells (Tfr cells) help regulate the immune response within germinal centers, where B cell maturation takes place. Whether Tfr cells are involved in the pathogenesis of multiple sclerosis (MS) remains unclear. Here, Martinez et al. show that the frequency of Tfr cells was increased in blood from patients with active MS.
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Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice | Communications Biology

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By Lea Rey, Jean-Paul Motta, Claude Knauf, Eric Espinosa, Meryem Aloulou, Nicolas Cenac, Matteo Serino, Nicolas Fazilleau, Louise Battut, Cyrielle Bories, Nadine Gheziel, Lionel Mouledous
| Nature Verified
Abstract Opioid-dependent immune-mediated analgesic effects have been broadly reported upon inflammation. In preclinical mouse models of intestinal inflammatory diseases, the local release of enkephalins (endogenous opioids) by colitogenic T lymphocytes alleviate inflammation-induced pain by down-modulating gut-innervating nociceptor activation in periphery.
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