D Briegas Morera

Background Digoxin is used to manage supraventricular arrhythmias and low output chronic heart failure (CHF). Due to its narrow therapeutic window, digoxin must be monitored clinically and pharmacokinetically. Blood levels below 0.6–0.8 ng/mL are infratherapeutic, but above 2–2.5 ng/mL serious gastrointestinal, cardiovascular, visual and neurological toxicity appears. Kidney failure and thyroid disease can trigger this phenomena.

Background Despite living in the high tech era, there is still a lack of software tools to help pharmacists to carry out their common tasks, pharmaceutical care being one of the most important. Purpose Designing a friendly intuitive application to gather, assess and use patients’ demographic and clinical information to obtain better results in pharmaceutical care. Material and methods We created a Filemaker database compatible with computers and tablets.

Background The antiretroviral combination tenofovir disoproxil, emtricitabine, cobicistat and elvitegravir (TDF/FTC/COBI/RVG) has been widely used to treat HIV infection. This regimen is related to the highest risk of kidney disease because of the ability of cobicistat to block creatinine tubular secretion, boosting tenofovir’s nephrotoxic effect because this drug is cleared using the same mechanism.