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D. M. Barch on Muck Rack

D. M. Barch

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A data-driven latent variable approach to validating the research domain criteria framework - Nature Communications

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By D. A. Fair, J. A. Mumford, D. M. Barch
| Nature Verified
Abstract Despite the widespread use of the Research Domain Criteria (RDoC) framework in psychiatry and neuroscience, recent studies suggest that the RDoC is insufficiently specific or excessively broad relative to the underlying brain circuitry it seeks to elucidate. To address these concerns, we employ a latent variable approach using bifactor analysis. We examine 84 whole-brain task-based fMRI (tfMRI) activation maps from 19 studies with 6192 participants.
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