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Introduction and aims of the study: Infertility is a common problem worldwide and defined as the failure to achieve a clinical pregnancy after 12 months of regular, unprotected intercourse. ZEB1 protein is a zinc-finger E homeobox-binding transcription factor. ZEB1 is ivolved in epithelial to mesenchymal transition (EMT) acting as a repressor of E-cadherin and other epithelial markers through signaling pathways as TGF-β and Wnt/β-catenin.
S. Stavros S. Stavros Affiliations Molecular Biology of Reproduction Unit and Recurrent Abortions Unit, Assisted Reproduction Unit, 1st Department of Obstetrics and Gynecology, School of Medicine, Alexandra General Hospital of Athens, National and Kapodistrian University of Athens, Athens, Greece Search for articles by this author L. Ntetsika L.
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