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Introduction As well-known heterocycles, furans play crucial roles in synthetic chemistry, medicine and materials science [1]. The compounds I which contain scaffold of furan and thioethers have displayed COX-2 inhibition (Fig 1, I) [1c]. Similarly, S-containing organic compounds also have significant influence on the synthsizing bioactive [2] and medicinal compounds [3], particularly used as candidate compounds for tumour, inflammation and Parkinsonism [4].
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