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D. Stave Kohtz on Muck Rack

D. Stave Kohtz

As seen in: BioRxiv
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Articles

Spheroid architecture strongly induces miR-221/222 expression and promotes oxidative phosphorylation and survival of mobile tumor cells through a mechanism that includes restriction of miR-9 expression

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By Avery Ward, Cody Hall, Maya O. Tree, D. Stave Kohtz
| BioRxiv
Abstract Tumor cell spheroids are three dimensional multicellular structures that form during the expansive growth of carcinoma cells. Spheroids support tumor metastasis as vehicles of dissemination, promoting growth and survival of bulk tumor and cancer stem cells within the mobile tumor cell population.
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