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Incorporating physiological and biochemical mechanisms into pharmacokinetic-pharmacodynamic models: a conceptual framework

Jun 19, 2023 |

By Gundert-Remy U, Karlsson MO, Dahl SG, Schneider YJ

| ncbi.nlm.nih.gov

Display options Abstract The aim of this conceptual framework paper is to contribute to the further development of the modelling of effects of drugs or toxic agents by an approach which is based on the underlying physiology and pathology of the biological processes.

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Incorporating physiological and biochemical mechanisms into pharmacokinetic-pharmacodynamic models: a conceptual framework

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