Damodara N. Reddy

Abstract TTK21 is a small molecule activator of p300/CBP acetyltransferase activity, which upon conjugation with glucose-derived carbon nanosphere (CSP) can efficiently cross the blood-brain barrier and activate histone acetylation in the brain. Its role in adult neurogenesis and retention of long-term spatial memory upon IP administration is well established. In this study, we have successfully demonstrated that CSP-TTK21 can be effectively administered via oral gavage.

Reactivity vs selectivity of quinone methides: Synthesis of pharmaceutically important molecules, toxicity and biological applications Quinone methides (QMs) are considered to be highly reactive intermediates because of their aromatization both in chemical and biological systems. Being highly accessible, quinone methides (QMs) have been widely exploited and their concurrent use has been manifested for the synthesis of tertiary and quaternary carbon centers of bioactives, drugs and like molecules.

Chemical synthesis of Torenia plant pollen tube attractant proteins by KAHA ligation† Nandarapu Kumarswamyreddy, ab Damodara N. Reddy, ac D. Miklos Robkis, a Nao Kamiya,d Ryoko Tsukamoto,d Masahiro M. Kanaoka, d Tetsuya Higashiyama, ade Shunsuke Oishi *a and Jeffrey W.