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Dana K Strode on Muck Rack

Dana K Strode

As seen in: Texas Medical Center
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"Protein Biomarkers GDF15 and FGF21 to Differentiate Mitochondrial Hepa" by Johan L K Van Hove, Marisa W Friederich et al.

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By Kristen Miller, Rohit Sharma, Marisa W Friederich, Dana K Strode
| Texas Medical Center
BACKGROUND: Mitochondrial hepatopathies (MHs) are primary mitochondrial genetic disorders that can present as childhood liver disease. No recognized biomarkers discriminate MH from other childhood liver diseases. The protein biomarkers growth differentiation factor 15 (GDF15) and fibroblast growth factor 21 (FGF21) differentiate mitochondrial myopathies from other myopathies. We evaluated these biomarkers to determine if they discriminate MH from other liver diseases in children.
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