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Danaë Giakoumakis on Muck Rack

Danaë Giakoumakis

As seen in: ACS Publications
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Articles

Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity

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By Ella Martin, Nicolò Bisi, Danaë Giakoumakis, Jone Paesmans
| ACS Publications
Synaptojanin1 (Synj1) is a dual activity phosphoinositide phosphatase that contains two catalytic domains: an N-terminal suppressor of actin 1-like (Sac1) domain and a central 5-phosphatase (5-PPase) domain. The protein additionally comprises a predicted RNA recognition motif and a C-terminal proline-rich domain required to mediate protein–protein interactions.
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