Case Report: A 23-year-old man was transferred to our hospital for management of injuries sustained when an e-cigarette exploded in his mouth, resulting in injuries and burns to his face, left hand, and chest. Before being transferred, he was stabilized and intubated for airway protection because of the possibility of inhalation injury. Computed tomography revealed comminuted fractures of his hard palate and nasal septum, with dislocation of adjacent teeth (Figure).