Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Daniel Espes
Liraglutide and Βeta-Cell Function in Young Adults With Long-Standing Type 1 Diabetes and Residual C-Peptide: A Blinded, Randomized Controlled Trial
1 Introduction Residual C-peptide secretion in long-standing T1D is prevalent and associated with improved metabolic stability, lower hypoglycemia risk and reduced complications [1-3], underscoring its clinical relevance beyond the early disease phase. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) can reduce body weight, insulin requirements and improve glycemic control in T1D and are increasingly used off-label [4-7].
Stem Cell-Based Therapy for Type 1 Diabetes
Nyckelord: MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Stem cell-derived islets; Induced pluripotent stem cells; Islet amyloid; Medicinsk vetenskap; Medical Science; Sammanfattning: Type 1 diabetes (T1D) is the most common chronic disease of children and adolescents and results from autoimmune-mediated destruction of pancreatic beta cells.
The role of the innate immune system in the development of type 1 diabetes
Nyckelord: MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Innate immunity; Histamine-1 Receptor Antagonist; Residual C-peptide; Proximity Extension Assay; Macrophage; Neutrophil; Positron Emission Tomography; Sammanfattning: Type 1 diabetes (T1D) is an autoimmune disease marked by beta-cell inflammation, known as insulitis, but its primary cause remains...
Investigations of hypoglycemic events and the role of GABA in type 1 diabetes
Nyckelord: MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; T1D; hypoglycemia; hypoglycemic events; CGM; GABA; clinical trial; beta-cell; Regenerative therapy; Medicinsk vetenskap; Medical Science; Sammanfattning: Introduction: Hypoglycemia in type 1 diabetes (T1D) ranges from mild to life-threatening events, yet most studies of hypoglycemia frequency rely on self-reported or aggregated data.
PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil - EJNMMI Research
[11C]FMZ was synthesized according to clinical routine at Uppsala University Hospital, as described previously [36]. Different batches of [11C]FMZ were delivered with molar activity at end of synthesis of approximately 300 MBq/nmol for PET imaging studies and approximately 150 MBq/nmol for in vitro experiments. For the PET/CT imaging study, one male pig (weight 24.5 kg) (Yorkshire x Swedish Landrace x Hampshire) was used.
Real-life data of hypoglycemic events in children and adolescents with type 1 diabetes
Discussion Our real-life CGM data clearly show that hypoglycemia is a frequent phenomenon among children and adolescents with T1D. Of great interest, a total of 11 740 serious hypoglycemic events (<3.0 mmol/L) were registered in the data set while only one severe hypoglycemic event was reported during the same time period.
Higher risk of severe hypoglycemia in children and adolescents with a rapid loss of C-peptide during the first 6 years after type 1 diabetes diagnosis
http://orcid.org/0000-0002-8502-8568Annika Grönberg1, http://orcid.org/0000-0001-8843-7941Daniel Espes2,3, Per-Ola Carlsson2,3, Johnny Ludvigsson4 1Department of Women's and Children's Health, Uppsala Universitet Institutionen for kvinnors och barns halsa, Uppsala, Sweden 2Department of Medical Sciences, Uppsala University, Uppsala, Sweden 3Science for Life Laboratory, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden 4Department of Biomedical and Clinical Scienses,...
Pregnancy induces pancreatic insulin secretion in women with long-standing type 1 diabetes
β-Cell function in women with L-T1D was recovered during gestation, but decreased after parturition To assess the effect of pregnancy on β-cell function, fasting and stimulated C-peptide were measured. First, it was evaluated whether C-peptide becomes measurable during pregnancy in comparison with NP individuals.
GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes
Emerging technologies, pharmacology and therapeutics GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes http://orcid.org/0000-0001-8843-7941Daniel Espes1,2, Hanna Liljebäck3,4, Henrik Hill5, Andris Elksnis3, José Caballero-Corbalan4, Per-Ola Carlsson3,4 1Department of Medical Cell Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden 2Department of Medical Sciences, Science for Life Laboratory, Uppsala University, Uppsala,...
Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans: A randomised crossover trial
Summary The hormone fibroblast growth factor 21 (FGF21) modulates tissue metabolism and circulates at higher levels in metabolic conditions associated with chronic sleep–wake disruption, such as type 2 diabetes and obesity. In the present study, we investigated whether acute sleep loss impacts circulating levels of FGF21 and tissue-specific production, and response pathways linked to FGF21.
Longitudinal Assessment of 11C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes
Pathophysiology Abstract The longitudinal alterations of the pancreatic β-cell and islet mass in the progression of type 1 diabetes (T1D) are still poorly understood. The objective of this study was to repeatedly assess the endocrine volume and the morphology of the pancreas for up to 24 months after T1D diagnosis (n = 16), by 11C-5-hydroxytryptophan (11C-5-HTP) positron emission tomography (PET) and MRI.
Better HbA1c during the first years after diagnosis of type 1 diabetes is associated with residual C peptide 10 years later
Clinical Care/Education/Nutrition Better HbA1c during the first years after diagnosis of type 1 diabetes is associated with residual C peptide 10 years later http://orcid.org/0000-0002-8502-8568Annika Grönberg1, Daniel Espes2,3, Per-Ola Carlsson2,3 1Department of Women’s and Children’s Health, Uppsala Universitet Institutionen for kvinnors och barns halsa, Uppsala, Sweden 2Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden 3Department of Medical Sciences, Uppsala...
Increased Interleukin-35 Levels in Patients With Type 1 Diabetes With Remaining C-Peptide
Increased Interleukin-35 Levels in Patients With Type 1 Diabetes With Remaining C-Peptide Daniel Espes, Kailash Singh, Stellan Sandler, Per-Ola Carlsson Diabetes Care Aug 2017, 40 (8) 1090-1095; DOI: 10.2337/dc16-2121
[11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes
[11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes Lina Carlbom, Daniel Espes, Mark Lubberink, Mats Martinell, Lars Johansson, Håkan Ahlström, Per-Ola Carlsson, Olle Korsgren, Olof Eriksson Diabetes May 2017, 66 (5) 1286-1292; DOI: 10.2337/db16-1449
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Daniel
Contact Daniel, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack