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Investigation of Inherited Noncoding Genetic Variation Impacting the Pharmacogenomics of Childhood Acute Lymphoblastic Leukemia Treatment

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By Kashi Raj Bhattarai, Kelly Barnett, Daniel Ferguson
| Texas Medical Center
Defining genetic factors impacting chemotherapy failure can help to better predict response and identify drug resistance mechanisms. However, there is limited understanding of the contribution of inherited noncoding genetic variation on inter-individual differences in chemotherapy response in childhood acute lymphoblastic leukemia (ALL).
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