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Daniel G. Barrus on Muck Rack

Daniel G. Barrus

As seen in: ACS Publications
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Articles

Development of Squaramides as Allosteric Modulators of the CB1 Receptor: Synthesis, Computational Studies, Biological Characterization, and Effects against Cocaine-Induced Behavioral Sensitization and Reinstatement in Rats

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By Thuy Anh Nguyen, Thụy Tường Nguyễn, Thủy Nguyễn, Ann M. Decker, Daniel G. Barrus, Jianfeng Liu
| ACS Publications
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Development of Squaramides as Allosteric Modulators of the CB1 Receptor: Synthesis, Computational Studies, Biological Characterization, and Effects against Cocaine-Induced Behavioral Sensitization and Reinstatement in Rats

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By Thuy Anh Nguyen, Thụy Tường Nguyễn, Thủy Nguyễn, Ann M. Decker, Daniel G. Barrus, Jianfeng Liu
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Axially Chiral Cannabinoids: Design, Synthesis, and Cannabinoid Receptor Affinity

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By Sara E. Kearney, Anghelo J. Gangano, Daniel G. Barrus, Kyle J. Rehrauer
| dx.doi.org
The resorcinol-terpene phytocannabinoid template is a privileged scaffold for the development of diverse therapeutics targeting the endocannabinoid system. Axially chiral cannabinols (axCBNs) are unnatural cannabinols (CBNs) that bear an additional C10 substituent, which twists the cannabinol biaryl framework out of planarity creating an axis of chirality.
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